PA5-28952 targets Aprataxin in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-28952 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 356 of Human Aprataxin.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
This gene encodes a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The encoded protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants has not been determined.
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Protein Aliases: AOA; AOA1; Aprataxin; AXA1; EAOH; EOAHA; FHA-HIT; Forkhead-associated domain histidine triad-like protein
Gene Aliases: AOA; AOA1; APTX; AXA1; EAOH; EOAHA; FHA-HIT
UniProt ID: (Human) Q7Z2E3
Entrez Gene ID: (Human) 54840