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Product Details
PA5-92422
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 93-342 of human APTX (NP_0011821781)
Conjugate
Form
Liquid
Concentration
0.47 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2806489
Product Specific Information
Immunogen sequence: LYPYIVEFEE EAKNPGLETH RKRKRSGNSD SIERDAAQEA EAGTGLEPGS NSGQCSVPLK KGKDAPIKKE SLGHWSQGLK ISMQDPKMQV YKDEQVVVIK DKYPKARYHW LVLPWTSISS LKAVAREHLE LLKHMHTVGE KVIVDFAGSS KLRFRLGYHA IPSMSHVHLH VISQDFDSPC LKNKKHWNSF NTEYFLESQA VIEMVQEAGR VTVRDGMPEL LKLPLRCHEC QQLLPSIPQL KEHLRKHWTQ; Positive Samples: 22Rv1, A-549, K-562, BT-474, U-87MG, HT-29, Raji; Cellular Location: Cytoplasm, Nucleus, nucleolus, nucleoplasm
Target Information
This gene encodes a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The encoded protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Aprataxin; FHA-HIT; Forkhead-associated domain histidine triad-like protein
Gene Aliases: AOA; AOA1; APTX; AXA1; EAOH; EOAHA; FHA-HIT
UniProt ID: (Human) Q7Z2E3
Entrez Gene ID: (Human) 54840
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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