Immunogen sequence: PRSSDLTDRV KVWTSGQVEE YDLDADDINS RVEMKPK
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%.
Aquaporin 1 is a 28kD integral membrane protein which was originally identified in red blood cells and renal proximal tubules. AQP1 is also expressed by the choroid plexus and various other tissues. It forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AQP-1; aquaporin 1 (channel-forming integral protein, 28kDa, CO blood group); aquaporin 1, Colton blood group antigen; Aquaporin-1; Aquaporin-CHIP; channel-like integral membrane protein, 28-kDa; Urine water channel; Water channel protein for red blood cells and kidney proximal tubule
Gene Aliases: AQP-CHIP; AQP1; CHIP28; CO
UniProt ID: (Human) P29972
Entrez Gene ID: (Human) 358
Molecular Function: transporter