MA1-20214 detects aquaporin 1 in human, mouse, and rat samples.
MA1-20214 has been successfully used in ELISA, immunohistochemistry (frozen and paraffin), and Western blot procedures.
The MA1-20214 immunogen is a synthetic peptide corrresponding to residues L(249) M I L M F S F F L P W L H N N H T I N K(269) of rat aquaporin 1.
Store at 4°C or -20°C if preferred, avoid freeze/thaw cycles.
Aquaporin 1 is a 28kD integral membrane protein which was originally identified in red blood cells and renal proximal tubules. AQP1 is also expressed by the choroid plexus and various other tissues. It forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AQP-1; Aquaporin 1 (aquaporin channel forming integral protein 28 (CHIP)); aquaporin 1 (channel-forming integral protein, 28kDa, CO blood group); aquaporin 1, Colton blood group antigen; Aquaporin-1; Aquaporin-CHIP; channel-like integral membrane protein, 28-kDa; Delayed early response protein 2; DER2; growth factor-induced delayed early response protein; Urine water channel; Water channel protein for red blood cells and kidney proximal tubule
Gene Aliases: AQP-CHIP; AQP1; CHIP28; CO
Molecular Function: transporter