In Western blot, bands can be seen ~28 kDa for the non-glycosylated form and ~37 kDa for the glycosylated form.
Suggested positive control: rat kidney, renal inner medulla.
Aquaporin 2 (AQP2) is a membrane protein involved in plasma membrane water transport in the renal collecting duct. This antibody is targeted to a peptide sequence upstream from the phosphorylated region that, upon phosphorylation, can diminish the antibody signal in immunoblots and immunocytochemistry.
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Protein Aliases: ADH water channel; AQP-2; AQP-CD; aquaporin 2 (collecting duct); Aquaporin-2; Aquaporin-CD; Collecting duct water channel protein; Water channel protein for renal collecting duct; water-channel aquaporin 2; WCH-CD
Gene Aliases: AQP-2; AQP-CD; AQP2; aquaporin-2; cph; jpk; WCH-CD
Molecular Function: transporter