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AQP3 is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 3 is localized at the basal lateral membranes of collecting duct cells in the kidney. In addition to its water channel function, aquaporin 3 has been found to facilitate the transport of nonionic small solutes such as urea and glycerol, but to a smaller degree. It has been suggested that water channels can be functionally heterogeneous and possess water and solute permeation mechanisms.
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Protein Aliases: 31.4 kDa water channel protein; AQP 3; AQP-3; Aquaglyceroporin-3; aquaporin 3 (GIL blood group); aquaporin 3 (Gill blood group); Aquaporin-3; Aquaporin3; Gill blood group
Gene Aliases: AQP-2; AQP-3; AQP3; GIL
UniProt ID: (Human) Q92482, (Bovine) Q08DE6, (Rat) P47862, (Mouse) Q8R2N1
Entrez Gene ID: (Human) 360, (Sheep) 443047, (Bovine) 780866, (Rat) 65133, (Mouse) 11828
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