Immunogen sequence: QLMIGCHLEQ PPPSNEEENV KLAHVKHKEQ I
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 87%.
AQP3 is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 3 is localized at the basal lateral membranes of collecting duct cells in the kidney. In addition to its water channel function, aquaporin 3 has been found to facilitate the transport of nonionic small solutes such as urea and glycerol, but to a smaller degree. It has been suggested that water channels can be functionally heterogeneous and possess water and solute permeation mechanisms.
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Protein Aliases: AQP 3; AQP-3; AQP3; Aquaglyceroporin-3; Aquaporin 3; aquaporin 3 (GIL blood group); Aquaporin-3
Gene Aliases: AQP-3; AQP3; GIL
UniProt ID: (Human) Q92482
Entrez Gene ID: (Human) 360
Molecular Function: transporter