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|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Synthetic peptide, corresponding to amino acids 301-318 of Rat Aquaporin 4.|
|Storage buffer||PBS with 0.1% BSA|
|Contains||0.1% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (Frozen) (IHC (F))||1:500-1:1000|
|Immunohistochemistry (Paraffin) (IHC (P))||1:500-1:1000|
|Western Blot (WB)||1:1000-1:10,000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (Paraffin) (IHC (P))||See 1 publications below|
MA1-34259 detects Aquaporin 4 from human samples. Does not cross react with mouse or rat.
MA1-34259 has been successfully used in immunohistochemistry (frozen tissue), immunohistochemistry (paraffin tissue), immunoprecipitation, ELISA, and Western blot applications. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
The MA1-34259 immunogen is synthetic peptide, corresponding to amino acids 301-318 of Rat Aquaporin 4.
Store at 4°C short term. For extended storage, aliquot and store at -20°C, avoiding freeze/thaw cycles.
The water-specific channel aquaporin 4 is located in various tissues including the gastro intestinal tract, kidney and brain. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Corpora amylacea in the brain form highly branched three-dimensional lattices.
MA1-34259 was used in immunohistochemistry - paraffin section to evaluate the three-dimensional morphology of corpora amylacea in the brain in normal aging
|Pirici I,Mărgăritescu C,Mogoantă L,Petrescu F,Simionescu CE,Popescu ES,Cecoltan S,Pirici D||Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie (55:1071)||2015|
aquaporin type4; HMIWC2; mercurial-insensitive water channel; MGC22454; MIWC
AQP4; MIWC; WCH4