This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: SLSLSERVAI IKGTYEPDED WEEQREERKK TMELTT
Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 75%.
Many isoforms of aquaporin have been identified in mammals, designated AQP0 through AQP10. Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell. Although most aquaporins are only permeable to water, AQP3, AQP7, AQP9 and one of the two AQP10 transcripts are also permeable to urea and glycerol. AQP2 is the only water channel that is activated by vasopressin to enhance water reabsorption in the kidney collecting duct. Aquaporins are involved in renal water absorption, generation of pulmonary secretions, lacrimation, and the secretion and reabsorption of cerebrospinal fluid and aqueous humor. In the lung, AQP5 is responsible for the majority of water transport across the apical membrane of type I alveolar epithelial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AQP 5; AQP-5; AQP5; Aquaporin 5; Aquaporin-5; Aquaporin5
Gene Aliases: AQP-5; AQP5; PPKB
UniProt ID: (Human) P55064
Entrez Gene ID: (Human) 362
Molecular Function: transporter