|Tested species reactivity||Bovine, Horse, Human, Mouse, Pig, Rabbit, Rat|
|Published species reactivity||Bovine, Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant full length human aromatase.|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage Conditions||-80° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||10-20 µg/ml|
|Western Blot (WB)||1-4 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-21398 detects aromatase in human, mouse, rat, bovine, horse, rabbit, and porcine samples.
PA1-21398 has been successfully used in immunohistochemistry (paraffin) and Western blot procedures.
The PA1-21398 immunogen corresponds to recombinant full length human aromatase.
Aromatase is a key enzyme in steroidogenesis and plays an important role in sexual differentiation, fertility, and carcinogenesis. many environmental chemicals may influence aromatase activity and thereby disrupt endocrine function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Aromatase enzyme expression in acromegaly and its possible relationship with disease prognosis.
PA1-21398 was used in immunohistochemistry to assess the relationship between aromatase expression and the clinical and prognostic features growth hormone secreting adenomas, prolactinomas, and normal pituitary tissues
|Selek A,Cetinarslan B,Gurbuz Y,Tarkun I,Canturk Z,Cabuk B||Endocrine (49:250)||2015|
Pathogen-associated molecular patterns initiate inflammation and perturb the endocrine function of bovine granulosa cells from ovarian dominant follicles via TLR2 and TLR4 pathways.
PA1-21398 was used in western blot to study the role of TLR2 and TLR4 in the initiation of inflammation and disturbance of bovine granulosa cell endocrine function by bacterial PAMPs
|Price JC,Bromfield JJ,Sheldon IM||Endocrinology (154:3377)||2013|