ARSB belongs to the sulfatase family. The arylsulfatase B homodimer hydrolyzes sulfate groups of N-Acetyl-D-galactosamine, chondriotin sulfate, and dermatan sulfate. The protein is targetted to the lysozyme. Mucopolysaccharidosis type VI is an autosomal recessive lysosomal storage disorder resulting from a deficiency of arylsulfatase B.
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Protein Aliases: ARSB; Arylsulfatase B; ASB; G4S; N-acetylgalactosamine-4-sulfatase
Gene Aliases: ARSB; ASB; G4S; MPS6
UniProt ID: (Human) P15848
Entrez Gene ID: (Human) 411
Molecular Function: hydrolase