Recommended positive controls: HeLa, HepG2, ARSB tansfected 293T cell, mouse placenta, rat testis.
Predicted reactivity: Dog (86%), Cat (89%), Bovine (90%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Arylsulfatase B encoded by this gene belongs to the sulfatase family. The arylsulfatase B homodimer hydrolyzes sulfate groups of N-Acetyl-D-galactosamine, chondriotin sulfate, and dermatan sulfate. The protein is targetted to the lysozyme. Mucopolysaccharidosis type VI is an autosomal recessive lysosomal storage disorder resulting from a deficiency of arylsulfatase B. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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Protein Aliases: Arylsulfatase B; Arylsulfatase B (MPS VI); arylsulfatase B complex; arylsulfatase B regulation; arylsulfatase B structural; arylsulfatase B temporal regulation; ASB; G4S; MPS6; N-acetylgalactosamine-4-sulfatase
Gene Aliases: 1110007C02Rik; AI480648; ARSB; As-1; As-1r; As-1s; As-1t; As1; As1-r; As1-s; As1-t; ASB; Asr-1; Ast-1; G4S; MPS6
Molecular Function: hydrolase