This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated. View Details
Aurora kinases belong to a highly conserved family of mitotic serine/threonine kinases with three members identified among mammals: Aurora A, B, and C. Studies on the temporal expression pattern and subcellular localization of Aurora kinases in mitotic cells suggest an association with mitotic structure. Aurora kinase functional influences span from G2 phase to cytokinesis and may be involved in key cell cycle events such as centrosome duplication, chromosome bi-orientation and segregation, cleavage furrow positioning, and ingression.
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Protein Aliases: AIK2; AIM1; ARK-3; ARK2; AURKB; Aurora 3; aurora B; Aurora kinase C; aurora-related kinase 3; Aurora/IPL1-related kinase 3; Aurora/IPL1/Eg2 protein 1; Aurora/IPL1/Eg2 protein 2; epididymis secretory protein Li 90; serine/threonine kinase 13 (aurora/IPL-like); serine/threonine kinase 13 (aurora/IPL1-like); Serine/threonine-protein kinase 13; Serine/threonine-protein kinase aurora-C; STK12; STK5
Gene Aliases: AIE1; AIE2; AIK3; AIRK3; ARK-3; ARK3; AurC; AURKC; aurora-C; HEL-S-90; IAK3; SPGF5; STK13
Molecular Function: non-receptor serine/threonine protein kinase