This Antibody was verified by Cell Treatment to ensure that the antibody binds to the antigen stated. View Details
Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases, members of the Ser/Thr protein kinase family, associate with microtubules during chromosome movement and segregation. Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. This protein is localized to centrosome from anaphase to cytokinesis. Expression is limited to testis in normal cells. Elevated expression levels are seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Aurora-C expression is maximum at M phase.
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Protein Aliases: AIE2; AIK3; ARK-3; ARK3; AurC; AURKC; Aurora 3; aurora B; Aurora kinase C; aurora-C; aurora-related kinase 3; Aurora/IPL1-related kinase 3; aurora/Ipl1/Eg2 protein 1; Aurora/IPL1/Eg2 protein 2; epididymis secretory protein Li 90; serine/threonine kinase 13 (aurora/IPL-like); serine/threonine kinase 13 (aurora/IPL1-like); Serine/threonine-protein kinase 13; Serine/threonine-protein kinase aurora-C; STK13
Gene Aliases: AIE1; AIE2; AIK3; AIRK3; ARK-3; ARK3; AurC; AURKC; aurora-C; HEL-S-90; IAK3; SPGF5; STK13
UniProt ID: (Human) Q9UQB9