|Tested species reactivity||Human|
|Published species reactivity||Rat, Human|
|Host / Isotype||Mouse / IgM, kappa|
|Immunogen||Human peripheral blood mononuclear cells|
|Purification||Ammonium sulfate precipitation|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||1-2 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 17 publications below|
MA5-12008 targets CD57 in FACS and IHC (P) applications and shows reactivity with Human samples.
The MA5-12008 immunogen is human peripheral blood mononuclear cells.
CD57 is expressed on a subpopulation of 15-20% of peripheral blood mononuclear cells, about 60% of NK active cells and on a subset of T cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Aberrant immunoarchitecture distinguishes hyperplastic germinal centres in pattern 1 angioimmunoblastic T-cell lymphoma from reactive follicles.
MA5-12008 was used in immunohistochemistry to study the immunological differences between germinal centres from pattern 1 angioimmunoblastic T-cell lymphoma and reactive lymphoid hyperplasia
|Tan LH,Tan SY||Hematological oncology (32:145)||2014|
Different morphology, stage and treatment affect immune cell infiltration and long-term outcome in patients with non-small-cell lung carcinoma.
MA5-12008 was used in immunohistochemistry to study the relationships between innate immune responses, adaptive immune responses and long-term prognosis in non-small cell lung cancer patients
|da Costa Souza P,Parra ER,Atanazio MJ,da Silva OB,Noleto GS,Ab'Saber AM,de Morais Fernezlian S,Takagaki T,Capelozzi VL||Histopathology (61:587)||2012|
NKT-associated hedgehog and osteopontin drive fibrogenesis in non-alcoholic fatty liver disease.
MA5-12008 was used in immunohistochemistry to study the roles of NK T-cell-associated hedgehog and osteopontin in the development of non-alcoholic fatty liver fibrosis
|Syn WK,Agboola KM,Swiderska M,Michelotti GA,Liaskou E,Pang H,Xie G,Philips G,Chan IS,Karaca GF,Pereira Tde A,Chen Y,Mi Z,Kuo PC,Choi SS,Guy CD,Abdelmalek MF,Diehl AM||Gut (61:1323)||2012|
Epithelioid angiosarcoma arising in schwannoma: report of three Chinese cases with review of the literature.
MA5-12008 was used in immunohistochemistry to report on three cases of epithelioid angiosarcoma arising in schwannoma
|Li C,Chen Y,Zhang H,Zheng X,Wang J||Pathology international (62:500)||2012|
Tumour eosinophilia combined with an immunohistochemistry panel is useful in the differentiation of type B3 thymoma from thymic carcinoma.
MA5-12008 was used in immunohistochemistry to investigate an immunohistochemistry method to distinguish type B3 thymoma from thymic carcinoma
|Khoury T,Chandrasekhar R,Wilding G,Tan D,Cheney RT||International journal of experimental pathology (92:87)||2011|
Characterization of cytotoxic immune response in skin and mucosal lesions of paracoccidioidomycosis.
MA5-12008 was used in immunohistochemistry to study the cytotoxic immune response in skin and mucosal lesions of paracoccidioidomycosis
|Pagliari C,Pereira NV,Kanashiro L,Stegun FW,Croda J,Duarte MI,Sotto MN||Journal of cutaneous pathology (37:565)||2010|
Biomolecular network reconstruction identifies T-cell homing factors associated with survival in colorectal cancer.
MA5-12008 was used in immunohistochemistry to use biomolecular network reconstruction to investigate the immune responses in colorectal cancer patients
|Mlecnik B,Tosolini M,Charoentong P,Kirilovsky A,Bindea G,Berger A,Camus M,Gillard M,Bruneval P,Fridman WH,Pagès F,Trajanoski Z,Galon J||Gastroenterology (138:1429)||2010|
Are CD57+ natural killer cells really important in early pregnancy failure?
MA5-12008 was used in immunohistochemistry to study whether CD57+ natural killer cells play a role in early pregnancy failure
|Ozcimen EE,Kiyici H,Uckuyu A,Yanik FF||Archives of gynecology and obstetrics (279:493)||2009|
Natural killer cells and alterations in collagen density: signs of periradicular herpesvirus infection?
MA5-12008 was used in immunohistochemistry to investigate the changes of natural killer cells and collagen density in specific type periodontitis and lesions
|Saboia-Dantas CJ,Coutrin de Toledo LF,Siqueira JF,Sampaio-Filho HR,Carvalho JJ,Pereira MJ||Clinical oral investigations (12:129)||2008|
Isolation of neural crest-derived stem cells from rat embryonic mandibular processes.
MA5-12008 was used in immunohistochemistry to characterize and isolate stem cells from embryonic mandibular processes in rats
|Zhang J,Duan X,Zhang H,Deng Z,Zhou Z,Wen N,Smith AJ,Zhao W,Jin Y||Biology of the cell (98:567)||2006|
Primary cutaneous histiocyte and neutrophil-rich CD30+ and CD56+ anaplastic large-cell lymphoma with prominent angioinvasion and nerve involvement in the forehead and scalp of an immunocompetent woman.
MA5-12008 was used in immunohistochemistry to report on a case of utaneous lymphoma of the head co-expressing CD56 and CD30
|Boudova L,Kazakov DV,Jindra P,Sima R,Vanecek T,Kuntscher V,Vera V,Bouda J,Michal M||Journal of cutaneous pathology (33:584)||2006|
Pulmonary large cell carcinoma with rhabdoid phenotype.
MA5-12008 was used in immunohistochemistry The report on a patient with pulmonary large cell carcinoma with rhabdoid phenotype
|Yilmazbayhan D,Ates LE,Dilege S,Gulluoglu M,Tanju S,Kalayci G||Annals of diagnostic pathology (9:223)||2005|
Pigmented solid-pseudopapillary neoplasm of the pancreas.
MA5-12008 was used in immunohistochemistry to report on a case of pigmented solid-pseudopapillary neoplasm of the pancreas
|Daum O,Sima R,Mukensnabl P,Vanecek T,Brouckova M,Benes Z,Michal M||Pathology international (55:280)||2005|
Lipomatous hemangiopericytoma of the head and neck: immunohistochemical and DNA ploidy analyses.
MA5-12008 was used in immunohistochemistry to characterize lipomatous hemangiopericytoma of the head and neck
|Alrawi SJ,Deeb G,Cheney R,Wallace P,Loree T,Rigual N,Hicks W,Tan D||Head and neck (26:544)||2004|
Natural killer and natural killer-T cells in psoriasis.
MA5-12008 was used in immunohistochemistry to study the roles of natural killer and natural killer-like T cells in psoriasis
|Cameron AL,Kirby B,Fei W,Griffiths CE||Archives of dermatological research (294:363)||2002|
Involvement of the Fas/FasL pathway in the pathogenesis of germ cell tumours of the adult testis.
MA5-12008 was used in immunohistochemistry to study the role of Fas/FasL signals in the pathogenesis of testis germ cell tumours
|Kersemaekers AM,van Weeren PC,Oosterhuis JW,Looijenga LH||The Journal of pathology (196:423)||2002|
Blisters in the small intestinal mucosa of coeliac patients contain T cells positive for cyclooxygenase 2.
MA5-12008 was used in immunohistochemistry to study the role of T cells positive for cyclooxygenase 2 in the small intestinal mucosa of coeliac patients
|Kainulainen H,Rantala I,Collin P,Ruuska T,Päivärinne H,Halttunen T,Lindfors K,Kaukinen K,Mäki M||Gut (50:84)||2002|