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|Tested species reactivity||Human|
|Published species reactivity||Human, Not Applicable|
|Host / Isotype||Mouse / IgM|
|Immunogen||Human neuroblastoma cells|
|Contains||0.09% sodium azide|
|Storage Conditions||4°C or -20°C if preferred|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1:50-1:100|
|Immunohistochemistry (Frozen) (IHC (F))||1:10 -1:100|
|Immunohistochemistry (Paraffin) (IHC (P))||1:10 -1:50|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
For FACS analysis, use 10ul of the suggested working dilution to label 1x10^6 cells in 100ul. A suggested positive control for immunohistochemical applications is human tonsil. This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections but sodium citrate buffer may enhance staining.
The protein encoded by this gene is a member of the glucuronyltransferase gene family. These enzymes exhibit strict acceptor specificity, recognizing nonreducing terminal sugars and their anomeric linkages. This gene product functions as the key enzyme in a glucuronyl transfer reaction during the biosynthesis of the carbohydrate epitope HNK-1 (human natural killer-1, also known as CD57 and LEU7). Alternate transcriptional splice variants have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
|Not Applicable||Not Cited||
Th1 but not Th17 cells predominate in the joints of patients with rheumatoid arthritis.
MA5-16948 was used in flow cytometry to quantify the prevalence of Th1 and Th17 cells in the joints of rheumatoid arthritis patients
|Yamada H,Nakashima Y,Okazaki K,Mawatari T,Fukushi JI,Kaibara N,Hori A,Iwamoto Y,Yoshikai Y||Annals of the rheumatic diseases (67:1299)||2008|
|Not Applicable||Not Cited||
Unique phenotype of human uterine NK cells and their regulation by endogenous TGF-beta.
MA5-16948 was used in immunohistochemistry to assess the expression of NK cell receptors and cytokines in the human endometrium
|Eriksson M,Meadows SK,Wira CR,Sentman CL||Journal of leukocyte biology (76:667)||2004|
Tropism of varicella-zoster virus for human tonsillar CD4(+) T lymphocytes that express activation, memory, and skin homing markers.
MA5-16948 was used in flow cytometry to report that Varicella-zoster virus infects human tonsillar CD4(+) T cells.
|Ku CC,Padilla JA,Grose C,Butcher EC,Arvin AM||Journal of virology (76:11425)||2002|
Beta-1,3-glucuronyltransferase 1; Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1; GlcAT-P; GLCATP; GlcUAT-P; GLCUATP; Glucuronosyltransferase P; HNK1; LEU7; LEU7 antigen; NK-1; NK1; UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase
B3GAT1; CD57; GLCATP; GLCUATP; HNK1; LEU7; NK-1; NK1