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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:2,000 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Mouse / IgG1 |
Class |
Monoclonal |
Type |
Antibody |
Clone |
OTI4E5 |
Immunogen |
Human recombinant protein fragment corresponding to amino acids 290-440 of human BAG5 produced in E.coli. |
Conjugate |
Unconjugated |
Form |
liquid |
Concentration |
1 mg/mL |
Purification |
Affinity chromatography |
Storage buffer |
PBS with 1% BSA, 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
It has been hypothesizes that the BAG-5 protein will induce the death of nigral neurons through its predicted interaction with hsp70, which will cause increased protein aggregation and cell death by disinhibition of hsp70's anti-apoptotic function. It is believed that BAG-5 will play an important role in the mechanisms of neuronal death. BAG-5 may also be of interest due to its possible role as a modulator of the hsp70/hsp40 chaperone axis or its possible interaction and coordination of localization/ modulation of other BAG containing proteins via BAG-BAG heterodimerization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BAG family molecular chaperone regulator 5; BAG-5; BAG-family molecular chaperone regulator-5; Bcl-2-associated athanogene 5; BCL2-associated athanogene 5
Gene Aliases: BAG-5; BAG5; KIAA0873
UniProt ID: (Human) Q9UL15
Entrez Gene ID: (Human) 9529
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