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|Tested species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (RDAYREAQQLVQR) corresponding to the internal amino acids of ADRBK1|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||0.3-1.0 ug/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody is predicted to react with bovine, canine, mouse, porcine and rat based on sequence homology.
The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
ADRBK1; adrenergic beta receptor kinase 1; adrenergic, beta, receptor kinase 1; BARK1; beta adrenergic receptor kinase 1; beta-ARK-1; BETA-ARK1; G-protein coupled receptor kinase 2; GRK2
ADRBK1; BARK; BARK1; BETA-ARK1; GRK2