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BBS4 Antibody (TA804560) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BBS4 (RC206210, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-BBS4. Positive lysates LY409788 (100 µg) and LC409788 (20 µg) can be purchased separately from OriGene.
Product Details
TA804560
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI2D5
Immunogen
Human recombinant protein fragment corresponding to amino acids 266-519 of human BBS4 produced in E.coli.
Conjugate
Form
liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
BBS4 contains tetratricopeptide repeats (TPR), similar to O-linked N-acetyglucosamine transferase. Mutations in the gene encoding this protein have been observed in patients with Bardet-Biedl syndrome type 4. BBS4 may play a role in pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Bardet-Biedl syndrome 4 protein
Gene Aliases: BBS4
UniProt ID: (Human) Q96RK4
Entrez Gene ID: (Human) 585
microtubule cytoskeleton organization
mitotic cytokinesis
neuron migration
neural tube closure
retina homeostasis
heart looping
negative regulation of systemic arterial blood pressure
spermatid development
visual perception
sensory perception of smell
negative regulation of gene expression
protein transport
dendrite development
regulation of lipid metabolic process
ventricular system development
striatum development
hippocampus development
cerebral cortex development
adult behavior
negative regulation of actin filament polymerization
melanosome transport
regulation of cytokinesis
protein localization to organelle
negative regulation of GTPase activity
microtubule anchoring at centrosome
nonmotile primary cilium assembly
social behavior
photoreceptor cell outer segment organization
negative regulation of appetite by leptin-mediated signaling pathway
positive regulation of multicellular organism growth
cilium assembly
fat cell differentiation
photoreceptor cell maintenance
positive regulation of cilium assembly
retinal rod cell development
intracellular transport
brain morphogenesis
sensory processing
centrosome organization
maintenance of protein location in nucleus
regulation of stress fiber assembly
cilium morphogenesis
regulation of cilium beat frequency involved in ciliary motility
face development
fat pad development
protein localization to cilium
protein localization to centrosome
regulation of nonmotile primary cilium assembly
protein localization to photoreceptor outer segment
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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