|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues S(71) W P C R N S Q S S E K A(83) of the long form of human Bcl-G.|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-4210 detects the long form of BCL-G in human samples.
PA1-4210 has been successfully used in Western blot procedures.
The PA1-4210 immunogen is a synthetic peptide corresponding to residues S(71) W P C R N S Q S S E K A(83) of the long form of human Bcl-G.
Bcl-G is a novel pro-apoptotic member of the Bcl-2 family. The human BCL-G gene encodes two proteins through alternative mRNA splicing, Bcl-G(L) (long) and Bcl-G(S) (short) consisting of 327 and 252 amino acids in length, respectively. Bcl-G(L) mRNA is expressed widely in adult human tissues, whereas Bcl-G(S) mRNA was found only in testis. Overexpression of Bcl-G(L) or Bcl-G(S) in cells induced apoptosis although Bcl-G(S) was far more potent than Bcl-G(L).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.