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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to a region within amino acids 1 and 45 of BCL3|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-28783 targets BCL3 in IF and WB applications and shows reactivity with Human samples.
The PA5-28783 immunogen is a synthetic peptide corresponding to a region within amino acids 1 and 45 of BCL3.
This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
B-cell leukemia/lymphoma 3; B-cell lymphoma 3-encoded protein; BCL-3; BCL4; chronic lymphatic leukemia protein; D19S37; proto-oncogene BCL3
BCL3; BCL4; D19S37