|Tested species reactivity||Human|
|Host / Isotype||Rat / IgG1|
|Immunogen||Recombinant human BCMA:Fc. The extracellular domain of human BCMA (residues 2-54) is fused to the Fc portion of human IgG1.|
|Storage buffer||tissue culture supernatant diluted in PBS|
|Contains||0.02% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1 µg/ml|
|Immunocytochemistry (ICC)||5 µg/ml|
|Immunofluorescence (IF)||5 ug/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-25953 detects BCMA from human samples.
MA1-25953 has been successfully used in immunocytochemistry and FACS procedures.
The MA1-25953 immunogen is recombinant human BCMA:Fc. The extracellular domain of human BCMA (residues 2-54) is fused to the Fc portion of human IgG1.
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.