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OriGene
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, the protein product of this gene (phakinin), and filensin, are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF). Mutations in this gene have been associated with juvenile-onset, progressive cataracts and Dowling-Meara epidermolysis bullosa simplex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 49 kDa cytoskeletal protein; beaded filament protein CP49; beaded filament structural protein 2, phakinin; bfps2, Cytoskeletal protein, 49-kD; lens fiber cell beaded filament protein CP 47; lens fiber cell beaded filament protein CP 49; lens intermediate filament-like light; MGC142078; MGC142080
Gene Aliases: CP47; CP49; CTRCT12; LIFL-L; PHAKOSIN
UniProt ID: (Human) Q13515
Entrez Gene ID: (Human) 8419
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