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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Purified human cIAP2.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 50% glycerol, 1mg/ml BSA|
|Contains||1.5mM sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1-3 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-26473 has been successfully used in Western blot procedures. By Western blot, this antibody detects a ~68 kDa band representing BIRC3 from Jurkat cell lysate
The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring finger domain. Transcript variants encoding the same isoform have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
API2; apoptosis inhibitor 2; baculoviral IAP repeat-containing 3; C-IAP2; cellular inhibitor of apoptosis 2; CIAP2; HAIP1; HIAP-1; HIAP1; IAP homolog; IAP homolog C; IAP-1; IAP1; inhibitor of apoptosis protein 1; mammalian IAP homolog C; RING finger protein 49; TNFR2-TRAF signaling complex protein; TNFR2-TRAF-signaling complex protein 1
AIP1; API2; BIRC3; c-IAP2; CIAP2; HAIP1; HIAP1; MALT2; MIHC; RNF49