MA1-91673 detects BNP from human samples.
MA1-91673 has been successfully used in Western blot and ELISA applications.
The MA1-91673 immunogen is: Synthetic peptide - amino acids 11-22 (FGRKMDRISSSS) corresponding to N terminal of Human BNP
This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The proteiNULLs biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BNP(1-28); BNP(1-29); BNP(1-30); BNP(1-32); BNP(2-31); BNP(3-29); BNP(3-30); BNP(3-32); BNP(4-27); BNP(4-29); BNP(4-30); BNP(4-31); BNP(4-32); BNP(5-29); BNP(5-31); BNP(5-32); Brain natriuretic peptide 32; brain type natriuretic peptide; Gamma-brain natriuretic peptide; natriuretic peptide precursor B; Natriuretic peptides B; natriuretic protein
Gene Aliases: BNP; NPPB
UniProt ID: (Human) P16860
Entrez Gene ID: (Human) 4879