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This gene belongs to the DAZ gene family required for germ cell development. It encodes an RNA-binding protein which is more similar to Drosophila Boule than to human proteins encoded by genes DAZ (deleted in azoospermia) or DAZL (deleted in azoospermia-like). Loss of this gene function results in the absence of sperm in semen (azoospermia). Histological studies demonstrated that the primary defect is at the meiotic G2/M transition. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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Protein Aliases: bol, boule-like; boule-like RNA binding protein; boule-like RNA-binding protein; Protein boule-like
Gene Aliases: BOLL; BOULE
UniProt ID: (Human) Q8N9W6
Entrez Gene ID: (Human) 66037
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