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Invitrogen
BRD8 Recombinant Rabbit Monoclonal Antibody (1H3L15)
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FIGURE: 1 / 7
BRD8 Antibody (702872) in ICC/IF
For immunofluorescence analysis, HCT 116 cells were fixed and permeabilized for detection of endogenous BRD8 using Anti-BRD8 Recombinant Rabbit Monoclonal Antibody (Product # 702872, 1:100 dilution) and labeled with Goat anti-Rabbit IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor Plus 488 conjugate (Product # A32731, 1:2000). Panel a) shows representative cells that were stained for detection and localization of BRD8 protein (green), Panel b) is stained for nuclei (blue) using ProLong™ Diamond Antifade Mountant with DAPI (P... View More
Product Details
702872
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
Expi293
Class
Recombinant Monoclonal
Type
Antibody
Clone
1H3L15
Immunogen
Protein corresponding to human BRD8 [aa1-aa200]
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2848219
Product Specific Information
This antibody is predicted to react with Mouse, Bovine.
Target Information
Transcriptional repressor that contribute to growth arrest during terminal macrophage differentiation by repressing target genes involved in Ras-dependent proliferation. Represses MMP1 promoter activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Bromodomain-containing protein 8; p120; Skeletal muscle abundant protein; Skeletal muscle abundant protein 2; Thyroid hormone receptor coactivating protein of 120 kDa; TrCP120
Gene Aliases: BRD8; p120; SMAP; SMAP2
UniProt ID: (Human) Q9H0E9
Entrez Gene ID: (Human) 10902
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
signal transduction
cell surface receptor signaling pathway
intracellular receptor signaling pathway
regulation of growth
histone H4 acetylation
histone H2A acetylation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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