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|Tested species reactivity||Human, Mouse|
|Published species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 239-268 amino acids from the central region of human BRS3|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Western Blot (WB)||See 1 publications below|
This antibody is predicted to react with rat based on sequence homology.
Mammalian bombesin-like peptides (see MIM 137260) are widely distributed in the central nervous system as well as in the gastrointestinal tract, where they modulate smooth-muscle contraction, exocrine and endocrine processes, metabolism, and behavior. They bind to G protein-coupled receptors on the cell surface to elicit their effects. Bombesin-like peptide receptors include gastrin-releasing peptide receptor (MIM 305670), neuromedin B receptor (MIM 162341), and bombesin-like receptor-3 (BRS3) (Ohki-Hamazaki et al., 1997).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Effect of bombesin receptor subtype-3 and its synthetic agonist on signaling, glucose transport and metabolism in myocytes from patients with obesity and type 2 diabetes.
PA5-26484 was used in western blot to study bombesin receptor subtype-3 in patients with obesity and type 2 diabetes
|González N,Martín-Duce A,Martínez-Arrieta F,Moreno-Villegas Z,Portal-Núñez S,Sanz R,Egido J||International journal of molecular medicine (35:925)||2015|
bombesin like receptor 3; bombesin receptor subtype 3; bombesin receptor subtype-3; bombesin-like receptor 3; BRS-3; G-protein coupled receptor
BB3; BB3R; BRS-3; BRS3