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Immunohistochemical analysis of CD157/Bone marrow stromal cell antigen 1 in formalin-fixed, paraffin-embedded human brain tissue using an isotype control antibody(top) and a CD157/Bone marrow stromal cell antigen 1 polyclonal antibody (Product # PA5-23388) (bottom) at 5 ug/ml.
|Tested species reactivity||Human, Primate|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide (51 CAEYRALLSPEQRNKN 66) of BST1 protein.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 0.05% BSA|
|Contains||0.05% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||5 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Bone marrow stromal cell antigen 1 (BST1) is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-Bcell growth. BST1, which is also known as ADP-rybosyl cyclase 2 and DAMP-1, is an enzyme which is expressed by BST1 gene in human. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal Bcell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
ADP-ribosyl cyclase 2; bone marrow stromal antigen 1; Bone marrow stromal cell antigen 1; BST-1; cADPr hydrolase 2; cyclic ADP-ribose hydrolase 2; NAD(+) nucleosidase; NAD+ nucleosidase