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Product Details
BEST3-1-BIOTIN
| Product Specifications | |
|---|---|
Species Reactivity |
Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Synthetic peptide taken within the last 50 amino acids from the C-terminus of rat Bestrophin-3 protein. |
Conjugate |
Biotin |
Form |
Liquid |
Concentration |
0.5-1.5 mg/mL |
Purification |
Affinity chromatography |
Storage buffer |
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Target Information
BEST3 belongs to the bestrophin family of anion channels, which includes BEST1, the gene mutant in vitelliform macular dystrophy (VMD), and 2 other BEST1-like genes, BEST2 and BEST4. Bestrophins are transmembrane (TM) proteins that share a homology region containing a high content of aromatic residues, including an invariant arg-phe-pro (RFP) motif. The bestrophin genes share a conserved gene structure, with almost identical sizes of the 8 RFP-TM domain-encoding exons and highly conserved exon-intron boundaries. Each of the 4 bestrophin genes has a unique 3-prime end of variable length.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Bestrophin-3; vitelliform macular dystrophy 2-like 3; Vitelliform macular dystrophy 2-like protein 3
Gene Aliases: Best3; mBest4; Vmd2l3
UniProt ID: (Mouse) Q6H1V1
Entrez Gene ID: (Mouse) 382427, (Rat) 314847
Molecular Function:
ion channel
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