|Western Blot (WB)||1-3 ug/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (RNYDYYASRVPESIK) corresponding to the C-terminus amino acids of BPNT1|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with mouse and rat based on sequence homology.
BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 3'(2'), 5'-bisphosphate nucleotidase 1; 3'(2'),5'-bisphosphate nucleotidase 1; bisphosphate 3'-nucleotidase; Bisphosphate 3'-nucleotidase 1; BPntase; epididymis luminal protein 20; PAP-inositol 1,4-phosphatase; PAP-inositol-1,4-phosphatase; PIP; testicular tissue protein Li 29
Gene Aliases: BPNT1; HEL20; PIP
UniProt ID: (Human) O95861
Entrez Gene ID: (Human) 10380
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