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PA1-29122 detects Bombesin from human samples.
PA1-29122 has been successfully used in immunohistochemistry (frozen tissue) and immunohistochemistry (paraffin tissue) applications.
The PA1-29122 immunogen is synthetic human gastrin releasing peptide (amino acid 14-27) coupled to BSA.
This gene encodes a member of the bombesin-like family of gastrin-releasing peptides. Its preproprotein, following cleavage of a signal peptide, is further processed to produce either the 27 aa gastrin-releasing peptide or the 10 aa neuromedin C. These smaller peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: bombesin; Gastrin-releasing peptide; GRP; GRP-10; GRP18-27; neuromedin C; Neuromedin-C; pre-progastrin releasing peptide; prepro-GRP; testicular tissue protein Li 103
Gene Aliases: GRP
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