MA5-17185 targets Brachyury protein T in FACS, IHC and WB applications and shows reactivity with Human samples.
The MA5-17185 immunogen is purified recombinant fragment of human T (amino acids: 257-309 ) expressed in E. Coli.
MA5-17185 detects Brachyury protein T which has a predicted molecular weight of approximately 47.4kDa.
The protein encoded by this gene is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells.
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Protein Aliases: Brachyury protein; Protein T; RP11-459F1.1; T brachyury homolog; T, brachyury homolog; T-box transcription factor T
Gene Aliases: SAVA; T; TBXT; TFT
UniProt ID: (Human) O15178
Entrez Gene ID: (Human) 6862