T (TBXT) The protein encoded by this gene is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells. Two transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: Brachyury protein; Protein T; T brachyury homolog; T, brachyury homolog; T-box transcription factor T; TFT
Gene Aliases: SAVA; T; TBXT; TFT
UniProt ID: (Human) O15178
Entrez Gene ID: (Human) 6862