Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: HTAFTKHSEEL GTEEGEVEEM DTLDPQTGLF YRSALTQSQS AKQQKLSQPP LEQTQLQVKT LQCFQTKQKQ TIHLQADQLQ HKLPQMPQLS IRHQKLTPLQ QEQAQPKPDV QHTQHPMVAK DRQLPTLMAQ PPQTVVQVLA VKTTQQL
Highest antigen sequence identity to the following orthologs - mouse 95%, rat 95%.
EMSY is a regulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin. Its interaction with BRCA2 suggests that it may play a central role in the DNA repair function of BRCA2. As part of a histone H3-specific methyltransferase complex may mediate ligand-dependent transcriptional activation by nuclear hormone receptors. Diseases associated with EMSY include Sporadic Breast Cancer and Breast Cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BRCA2-interacting transcriptional repressor EMSY; EMSY BRCA2-interacting transcriptional repressor; EMSY protein; EMSY, BRCA2-interacting transcriptional repressor; FLJ90741; protein EMSY
Gene Aliases: C11orf30; EMSY; GL002
UniProt ID: (Human) Q7Z589
Entrez Gene ID: (Human) 56946
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support