Recommended positive controls: U87-MG.
Predicted reactivity: Mouse (83%), Rat (83%), Rhesus Monkey (97%), Bovine (86%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway, recognizes and binds to proteins bearing specific amino-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: N-recognin-7; Putative E3 ubiquitin-protein ligase UBR7; RING-type E3 ubiquitin transferase UBR7
Gene Aliases: C14orf130; UBR7
UniProt ID: (Human) Q8N806
Entrez Gene ID: (Human) 55148