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Product Details
26094-1-AP
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
C15orf27 Fusion Protein Ag23390 (1-347 aa encoded by BC104953)
Conjugate
Form
Liquid
Concentration
0.32 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MVASTVANG PRSPWDAISL IIMLRIWRVK RVIDAYVLPV KLEMEMVIQQ YEKAKVIQDE QLERLTQICQ EQGFEIRQLR AHLAQQDLDL AAEREAALQA PHVLSQPRSR FKVLEAGTWD EETAAESVVE ELQPSQEATM KDDMNSYISQ YYNGPSSDSG VPEPAVCMVT TAAIDIHQPN ISSDLFSLDM PLKLGGNGTS ATSESASHSS VTRAQSDSSQ TLGSSMDCST AREEPSSEPG PSPLPLPSQQ QVEEATVQDL LSSLSEDPCP SQKALDPAPL ARPSPAGSAQ TSPELEHRVS LFNQKNQEGF TVFQIRPVIH FQPTVPMLED KFRSLESKEQ KLHRVPEA (1-347 aa encoded by BC104953)
Target Information
C15orf27 is a voltage-sensor protein present on the post-synaptic side of glutamatergic mossy fibers and granule cells in the cerebellum. Despite the presence of a voltage-sensor segment, it does not form a functional ion channel and its precise role remains unclear. The protein undergoes both rapid and slow structural rearrangements in response to changes in voltage, and contains a zinc-binding site that can regulate the slow conformational transition.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HsHVRP1; hTMEM266; Hv1 related protein 1; HV1-related protein 1; Transmembrane protein 266; transmembrane protein C15orf27; transmembrane protein C15orf27 homolog
Gene Aliases: 9630029F15; C15orf27; HVRP1; TMEM266
UniProt ID: (Mouse) Q8BZB3, (Human) Q2M3C6
Entrez Gene ID: (Mouse) 244886, (Human) 123591
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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