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Product Details
PA5-59788
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human C15orf27. Recombinant protein control fragment (Product #RP-98127).
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2638777
Product Specific Information
Immunogen sequence: SLSEDPCPSQ KALDPAPLAR PSPAGSAQTS PELEHRVSLF NQKNQEGFTV FQIRPVIHFQ PTVPMLEDKF RSLESKEQKL HRV^M
^M
Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 78%.
Target Information
C15orf27 is a voltage-sensor protein present on the post-synaptic side of glutamatergic mossy fibers and granule cells in the cerebellum. Despite the presence of a voltage-sensor segment, it does not form a functional ion channel and its precise role remains unclear. The protein undergoes both rapid and slow structural rearrangements in response to changes in voltage, and contains a zinc-binding site that can regulate the slow conformational transition.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HsHVRP1; hTMEM266; Hv1 related protein 1; HV1-related protein 1; Transmembrane protein 266; transmembrane protein C15orf27
Gene Aliases: C15orf27; HVRP1; TMEM266
UniProt ID: (Human) Q2M3C6
Entrez Gene ID: (Human) 123591
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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