Immunogen sequence: SEPQFVQFNG GFSQEQLNWL NEVLTFSDTN QEKVVIVSHL PIYPDASDNV CLAWNYRDAL AVIWSHECVV CFFAGHTHDG GYSEDPFGVY HVNLEGVIET APDSQAFGTV HVYPDKMMLK GRGRVPDRIM NYKKERAFHC; Positive Samples: Mouse lung, Mouse spleen, Rat brain, Rat lung
Hydrolyzes ADP-ribose, IDP-ribose, CDP-glycerol, CDP-choline and CDP-ethanolamine, but not other non-reducing ADP-sugars or CDP-glucose. May be involved in immune cell signaling as suggested by the second-messenger role of ADP-ribose, which activates TRPM2 as a mediator of oxidative/nitrosative stress.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ADP-ribose/CDP-alcohol pyrophosphatase; ADPRibase-Mn; CDP-choline phosphohydrolase; liver manganese (II)-dependent ADP-ribose/CDP-alcohol pyrophosphatase; Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase
Gene Aliases: 2310004I24Rik; ADPRibase-Mn; Adprm; MDS006; RGD1309906