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C19orf10 Antibody (PA5-106865) in IHC (P)
Immunohistochemistry analysis of C19orf10 in human colorectal cancer. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with C19orf10 polyclonal antibody (Product # PA5-106865) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-106865
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human MYDGF(Accession Q969H8), corresponding to amino acid residues S50-K100.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2854529
Product Specific Information
Antibody detects endogenous levels of total C19orf10.
Target Information
The interleukins are a broad family of well characterized cytokines, primarily of hematopoietic cell origin. Cytokines are small, soluble proteins with pleiotropic effects on a variety of cell types. Cytokines have a regulatory function over the immune system and mediate aspects of inflammatory response. IL-25 (also called SF20/IL-25) is a secreted bone marrow stroma-derived growth factor cytokine that is derived from Th2 T-cells. IL-25 belongs to the IL-17 cytokine family and is capable of amplifying allergic type inflammatory responses by its actions on other cell types. IL-25 binds to mouse thymic shared antigen-1 and supports lymphoid cell proliferation. Infusion of mice with IL-25 induces IL-4, IL-5, and IL-13 gene expression. IL-25 induced mice also develop epithelial cell hyperplasia, increased mucus secretion, and airway hyperreactivity, suggesting that IL-25 may be an important mediator of allergic disease via production of IL-4, IL-5, IL-13 and eotaxin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CS010; IL 25; IL 27; interleukin 25; interleukin 27 working designation; interleukin-25; Interleukin25; MYDGF; Myeloid-derived growth factor; R33729 1; R337291; similar to lymphocyte antigen 6 complex, locus E ligand; stromal cell-derived growth factor SF20; UPF0556 protein C19orf10; UPF0556 protein C19orf10 homolog
Gene Aliases: C19orf10; D17Wsu104e; EUROIMAGE1875335; IL25; IL27; IL27w; Ly6elg; MYDGF; R33729_1; SF20
UniProt ID: (Human) Q969H8, (Mouse) Q9CPT4
Entrez Gene ID: (Rat) 501282, (Human) 56005, (Mouse) 28106
positive regulation of endothelial cell proliferation
positive regulation of angiogenesis
angiogenesis
positive regulation of protein phosphorylation
apoptotic process
positive regulation of phosphatidylinositol 3-kinase signaling
IRE1-mediated unfolded protein response
negative regulation of apoptotic process
positive regulation of MAPK cascade
positive regulation of transcription from RNA polymerase II promoter
positive regulation of protein kinase B signaling
cellular response to brefeldin A
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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