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Adding 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
Positive Control - WB: human PC-3 whole cell, human HEK293 whole cell, human K562 whole cell. IHC: human breast cancer tissue, human lymphoma tissue, human endometrial cancer tissue. ICC/IF: PC-3 cell. Flow: MCF-7 cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
TIMM29, also known as C19orf52, is identified as a novel subunit of the human TIM22 complex, which plays a critical role in the mitochondrial inner membrane. This protein is crucial for the stability of the TIM22 complex, which is responsible for the translocation of hydrophobic inner mitochondrial membrane proteins carrying internal targeting signals. TIMM29/C19orf52 is integrated into the mitochondrial inner membrane, exposing its C-terminus to the intermembrane space, and is vital for mitochondrial function and protein import pathways. This gene's importance is underscored by its involvement in processes related to mitochondrial integrity and its potential role in neurodegenerative disorders and viral interactions, such as those with the hepatitis B virus (HBV).
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Protein Aliases: Mitochondrial import inner membrane translocase subunit Tim29; TIM29
Gene Aliases: c19orf52; TIMM29
UniProt ID: (Human) Q9BSF4
Entrez Gene ID: (Human) 90580
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