OriGene

C1S Monoclonal Antibody (OTI4E3), TrueMAB™

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C1S Antibody in Immunocytochemistry (ICC/IF) — Anti-C1S mouse monoclonal antibody (TA504082) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY C1S(RC218963).

C1S Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical staining of paraffin-embedded human Kidney tissue within the normal limits using anti-C1S mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, TA504082)

C1S Antibody in Western Blot (WB) — HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY C1S (RC218963, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-C1S. Positive lysates LY400655 (100 µg) and LC400655 (20 µg) can be purchased separately from OriGene.

C1S Antibody in Flow Cytometry (Flow) — Flow cytometric analysis of Jurkat cells, using anti-C1S antibody (TA504082), (Red), compared to a nonspecific negative control antibody, (Blue).

Product Details

TA504082

Applications	Tested Dilution	Publications
Western Blot (WB)	1:2,000	-
Immunohistochemistry (Paraffin) (IHC (P))	1:150	-
Immunocytochemistry (ICC/IF)	1:100	-
Flow Cytometry (Flow)	1:100	-

Product Specifications
Species Reactivity	Human
Host/Isotype	Mouse / IgG2a
Class	Monoclonal
Type	Antibody
Clone	OTI4E3
Immunogen	Full length human recombinant protein of human C1S produced in HEk293T cell. View antigen
Conjugate	Unconjugated
Form	liquid
Concentration	1 mg/mL
Purification	Affinity chromatography
Storage buffer	PBS with 1% BSA, 50% glycerol
Contains	0.02% sodium azide
Storage conditions	-20° C, Avoid Freeze/Thaw Cycles

Target Information

This gene encodes a serine protease, which is a major constituent of the human complement subcomponent C1. C1s associates with two other complement components C1r and C1q in order to yield the first component of the serum complement system. Defects in this gene are the cause of selective C1s deficiency.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: basic proline-rich peptide IB-1; C1 esterase; Complement C1s subcomponent; Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain; Complement component 1 subcomponent s

Gene Aliases: C1S

UniProt ID: (Human) P09871

Entrez Gene ID: (Human) 716

Molecular Function: serine protease