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Enables erythropoietin receptor binding activity. Involved in erythropoietin-mediated signaling pathway and positive regulation of erythrocyte differentiation. Located in plasma membrane. RHEX (Regulator Of Hemoglobinization And Erythroid Cell Expansion) is a Protein Coding gene. Diseases associated with RHEX include Gallbladder Benign Neoplasm and Gallbladder Adenoma. Acts as a signaling transduction factor of the EPO-EPOR signaling pathway promoting erythroid cell differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Regulator of hemoglobinization and erythroid cell expansion protein; Regulator of human erythroid cell expansion protein; uncharacterized protein C1orf186; unnamed protein product
Gene Aliases: C1orf186; RHEX
UniProt ID: (Human) Q6ZWK4
Entrez Gene ID: (Human) 440712
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