|Immunohistochemistry (Frozen) (IHC (F))||1:20-1:200|
|Tested Species reactivity||Human|
|Host / Isotype||Sheep / IgG|
|Immunogen||Human C4BP purified from plasma|
|Storage buffer||glycine buffered saline with 0.01% benzamidine, 0.1% EACA, 1mM EDTA|
|Contains||0.09% sodium azide|
|Storage conditions||4°C or -20°C if preferred|
This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. Along with a single, unique beta-chain, seven identical alpha-chains encoded by this gene assemble into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Two pseudogenes of this gene are also found in the cluster.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C4b-binding protein alpha chain; C4bp; Proline-rich protein; PRP; RP11-164O23.4, C4BP, PRP,C4b-binding protein alpha chain
Gene Aliases: C4BP; C4BPA; PRP
UniProt ID: (Human) P04003
Entrez Gene ID: (Human) 722
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