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|Tested species reactivity||Human|
|Host / Isotype||Sheep / IgG|
|Immunogen||Human C4BP purified from plasma|
|Storage buffer||glycine buffered saline with 0.01% benzamidine, 0.1% EACA, 1mM EDTA|
|Contains||0.09% sodium azide|
|Storage Conditions||4°C or -20°C if preferred|
|Tested Applications||Dilution *|
|Immunohistochemistry (Frozen) (IHC (F))||1:20-1:200|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. Along with a single, unique beta-chain, seven identical alpha-chains encoded by this gene assemble into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Two pseudogenes of this gene are also found in the cluster.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
C4b-binding protein alpha chain; C4bp; Proline-rich protein; PRP; RP11-164O23.4, C4BP, PRP,C4b-binding protein alpha chain
C4BP; C4BPA; PRP