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|Tested species reactivity||Bovine, Ferret, Human, Mink, Rabbit|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||C5aR - peptide: Met1 - Asn31|
|Contains||0.09% sodium azide|
|Storage Conditions||4°C or -20°C if preferred|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1:50-1:100|
|Functional Assay (FN)||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Predicted to react with mustelid based on sequence homology.
For FACS analysis, use 10ul of the suggested working dilution to label 1x10^6 cells in 100ul.
CD88 is a 45kDa G-protein coupled cell surface receptor, also known as C5aR. The CD88 molecule functions as a receptor for the complement component C5a, which is a potent proinflammatory molecule and a chemoattractant for neutrophils to sites of infection. In mouse, CD88 is expressed on granulocytes, monocytes and macrophages but not on resting or stimulated lymphocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
C5A; C5a anaphylatoxin chemotactic receptor-like; C5a anaphylatoxin receptor; C5a ligand; C5a Receptor; C5a-R; C5AR; C5R1; complement component 5 receptor 1
C5A; C5AR; C5AR1; C5R1; CD88