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|Tested species reactivity||Human|
|Host / Isotype||Rat / IgG2a|
|Immunogen||RBL-2H3 (rat basophilic leukemia) transfected cells expressing human C5aR on the cell surface|
|Storage buffer||PBS with 4-5mg/ml BSA|
|Contains||0.02% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-17741 targets C5a receptor/CD88 in FACS applications and shows reactivity with Human samples.
The MA5-17741 immunogen is rBL-2H3 (rat basophilic leukemia) transfected cells expressing human C5aR on the cell surface.
C5a Anaphylatoxin Receptor mediates the effects of one of the most potent chemotactic agents known, in a wide variety of inflammatory cell types. C5a receptor 1 has been implicated in asthma. C5a receptor 1 expression has been reported in myeloid blood cells, brain, liver, lung, spleen, heart, kidney, and intestinal tract. ESTs have been isolated from B-cell/lung/testis, nerve, and placenta libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
C5A; C5a anaphylatoxin receptor; C5a ligand; C5a receptor; C5a-R; C5AR; C5AR1; C5R1; CD88 antigen; complement component 5 receptor 1
C5A; C5AR; C5AR1; C5R1; CD88