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Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: CGPGEHGQRI EWRKWKQQKK EEKKKWKDLK LMKKLERQRA QEEQAKRLEE EEAAAEKEDR GRPYTLS
C9orf114 is a protein coding gene. Required for association of the centrosomes with the poles of the bipolar mitotic spindle during metaphase. Also involved in chromosome alignment. May promote centrosome maturation probably by recruiting A-kinase anchor protein AKAP9 to centrosomes in early mitosis. Binds specifically to miRNA MIR145 hairpin, regulates MIR145 expression at a postranscriptional level.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CENP-32; Centromere protein 32; Kinetochore-associated protein; Putative methyltransferase C9orf114; SPOUT domain-containing methyltransferase 1
Gene Aliases: C9orf114; CENP-32; HSPC109; SPOUT1
UniProt ID: (Human) Q5T280
Entrez Gene ID: (Human) 51490
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