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Product Details
H00055684-M01
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
2E11-1F10
Immunogen
C9orf86 (AAH02945, 1 a.a. approximately 477 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.22 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Immunogen sequence: MKIVIRGDRN TGKTALWHRL QGRPFVEEYI PTQEIQVTSI HWSYKTTDDI VKVEVWDVVD KGKCKKRGDG LKMENDPQEA ESEMALDAEF LDVYKNCNGV VMMFDITKQW TFNYILRELP KVPTHVPVCV LGNYRDMGEH RVILPDDVRD FIDNLDRPPG SSYFRYAESS MKNSFGLKYL HKFFNIPFLQ LQRETLLRQL ETNQLDMDAT LEELSVQQET EDQNYGIFLE MMEARSRGHA SPLAANGQSP SPGSQSPVVP AGAVSTGSSS PGTPQPAPQL PLNAAPPSSV PPVPPSEALP PPACPSAPAP RRSIISRPPP WGWRLRGALG RRGQWPPWGG GRACHCLGRH LPLYHRLCRC PVAAVCASEL EEAGHWWSPG WALQVLGLQA QCEPALQEGR GQLASARLGG HPGPLGAEPP VFLRDVTEAQ EGPVRVCLQR LGRGRLAVGC ALPRHLLALR AHLGPQHAYG SASGREP
Target Information
Maternal embryonic leucine-zipper kinase (MELK) is a key regulator of survival of stemlike GBM cells in vitro. MELK expression is increased in breast cancer tissue and this increase is also associated with poor patient survival, as predicted for a candidate oncogene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GTP-binding protein Parf; Partner of ARF; putative GTP-binding protein Parf; Rab-like GTP-binding protein 1C; Rab-like protein 1; Rab-like protein 6; RBEL1
Gene Aliases: C9orf86; PARF; pp8875; RABL6; RBEL1
UniProt ID: (Human) Q3YEC7
Entrez Gene ID: (Human) 55684
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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