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Invitrogen
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Recombinant Monoclonal |
Type |
Antibody |
Clone |
ARC1269 |
Immunogen |
A synthesized peptide derived from human p60 CAF1 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.25 mg/mL |
Purification |
Protein A |
Storage buffer |
PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
Contains |
0.02% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2849535 |
Chromatin assembly factor 1 (CAF-1) is a member of the histone chaperone family. It is required for inheritance of epigenetically determined chromosomal states, and in vitro, it promotes the assembly of chromatin during DNA replication and DNA repair. CAF-1 is a complex of three subunits; p150, p60, and p48. This complex is localized to the nucleus of human cells. Both the composition and the biochemical activity of CAF-1 are conserved among human, yeast, and Drosophila.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CAF-1 subunit B; CAF-I 60 kDa subunit; CAF-I p60; CAF1 p60; Chromatin assembly factor 1 subunit B; Chromatin assembly factor I p60 subunit; human chromatin assembly factor-I p60 subunit; M-phase phosphoprotein 7; p60 CAF1; p60-CAF1
Gene Aliases: CAF-1; CAF-IP60; CAF1; CAF1A; CAF1P60; CHAF1B; MPHOSPH7; MPP7
UniProt ID: (Human) Q13112
Entrez Gene ID: (Human) 8208
Molecular Function:
chromatin/chromatin-binding, or -regulatory protein
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