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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 52-82 amino acids from the N-terminal region of human CAMKK2|
|Purification||Ammonium sulfate precipitation, Size-exclusion - Dialysis|
|Contains||0.09% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
CAMKK2 belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. CAMKK2 appears to be involved in hippocampal activation of CREB1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
calcium/calmodulin-dependent protein kinase beta; calcium/calmodulin-dependent protein kinase kinase 2, beta; caM-kinase kinase 2; CaM-kinase kinase beta; caM-KK 2; CaM-KK beta; CaMKK beta; CAMKK beta protein; CAMKK2; CAMKKB; KIAA0787
CAMKK; CAMKK2; CAMKKB; KIAA0787