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|Tested species reactivity||Human, Mouse, Primate, Rat|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified recombinant fragment of human CARM1 expressed in E. Coli.|
|Contains||0.03% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1/200 - 1/400|
|Immunofluorescence (IF)||1/200 - 1/1000|
|Immunohistochemistry (IHC)||1/200 - 1/1000|
|Western Blot (WB)||1/500 - 1/2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-15796 targets CARM1 in FACS, IF, IHC, and WB applications and shows reactivity with Human, Non-human primate, Mouse and Rat samples.
The MA5-15796 immunogen is purified recombinant fragment of human CARM1 expressed in E. Coli.
MA5-15796 detects CARM1 which has a predicted molecular weight of approximately 65kDa.
Protein arginine N-methyltransferases, such as CARM1, catalyze the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation has been implicated in signal transduction, metabolism of nascent pre-RNA, and transcriptional activation. Tissue specificity: Overexpressed in prostate adenocarcinomas and high-grade prostatic intraepithelial neoplasia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
coactivator-associated arginine methyltransferase 1; coactivator-associated arginine methyltransferase 1 variant 5; histone-arginine methyltransferase CARM1; PRMT4, histone-arginine methyltransferase CARM1; protein arginine methyltransferase; protein arginine N-methyltransferase 4